The recommended initial daily dose is 25 to 100 mg of ALDACTONE administered in either single or divided doses is recommended. Dosage can be titrated at two-week intervals. Doses greater than 100 mg/day generally do not provide additional reductions in blood pressure.
Usual Adult Dose for Edema 25 to 200 mg orally per day in single or divided doses Duration of therapy: When given as the sole diuretic, continue the initial dose for at least 5 days, after which the initial dose may be adjusted to an optimal maintenance dose.
Initial dose: 20 to 80 mg orally once; may repeat with the same dose or increase by 20 or 40 mg no sooner than 6 to 8 hours after the previous dose until the desired diuretic effect has been obtained. Maintenance dose: Administer the dose that provided the desired diuretic effect once or twice a day (e.g., at 8 am and 2 pm).
20 mg PO qDay; if initial 20 mg dose is tolerated, dosage can be increased to 37.5 mg as clinically indicated; Hypokalemia. Range: 25-100 mg PO qDay. Hirsutism (Off-label) Women with hirsutism. 50-200 mg PO qDay or divided q12hr. Acne (Off-label) Females with hormonal acne. 50-200 mg PO qDay or divided q12hr. Dosing Modifications Renal impairment
For oral dosage form (tablets): Adults—At first, 25 to 100 milligrams (mg) per day, taken in either single or divided doses. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day.
Therapy should be individualized according to patient response to gain maximal therapeutic response and to determine the minimal dose needed to maintain that response. Adults — The usual initial dose of LASIX is 20 mg to 80mg given as a single dose. Ordinarily a prompt diuresis ensues.
CrCl greater than or equal to 50 mL/min/1.73 m²: 12.5-25 mg once/day; use maintenance dose of 25 mg once/day or every 12 hours after 4 weeks of treatment with potassium less than or equal to 5 mEq/ L
Aldactone (spironolactone) is a prescription tablet used to treat heart failure, high blood pressure, and other conditions. Learn about side effects and more.
ALDACTONE is administered at a daily dosage of 400 mg for three to four weeks. Correction of hypokalemia and of hypertension provides presumptive evidence for the diagnosis of primary hyperaldosteronism.
Spironolactone is a medicine used in a variety of heart-related and fluid-retaining conditions. It is also used for the diagnosis and management of primary hyperaldosteronism (a condition where the adrenal glands produce too much of the hormone aldosterone leading to low potassium levels and a more alkaline blood pH).